Overview |
SMB is a scalable chromatographic technology that simulates the counter current motion of the solids stationary phase against the liquid eluent. SMB technology is used today for continuous chromatographic separations at the commodity scale. For example, parrafins are separated from kerosine to produce straight run Jet A fuel, sugar is purified, and xylenes are purified using an SMB among many other commodity examples. The BioProcessing Separations Consortium is pushing the state of the art in SMB technology by undertaking research in advanced modes of SMB operation such Expand Bed Adsorption (EBA-SMB), reactive SMBs, and unique column configurations to enable new applications of SMB technology in traditionally difficult to handle bioprocess streams. |